Macrocarpal A

Names

[ Name ]:
Macrocarpal A

[Synonym ]:
1,3-Benzenedicarboxaldehyde, 5-[(1R)-1-[(1aR,4R,4aR,7S,7aS,7bR)-decahydro-4-hydroxy-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxy-
2,4,6-trihydroxy-5-{(1R)-1-[(1aR,4R,4aR,7S,7aS,7bR)-4-hydroxy-1,1,4,7-tetramethyldecahydro-1H-cyclopropa[e]azulen-7-yl]-3-methylbutyl}benzene-1,3-dicarbaldehyde
macrocarpal A
2,4,6-Trihydroxy-5-{(1R)-1-[(1aR,4R,4aR,7S,7aS,7bR)-4-hydroxy-1,1,4,7-tetramethyldecahydro-1H-cyclopropa[e]azulen-7-yl]-3-methylbutyl}isophthalaldehyde

Biological Activity

[Description]:

Macrocarpal A (10-epi-Eucarobustol F) is an antibacterial agent isolated from the leaves of Eucalyptus macrocarpa. Macrocarpal A inhibits the growth of Bacillus subtilis PCI219 (minimum inhibitory concentration below 0.2 µM) and Staphylococcus aureus FDA209P (minimum inhibitory concentration is 0.4 µM)[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Murata M, et al. Macrocarpal A, a novel antibacterial compound from Eucalyptus macrocarpa[J]. Agricultural and biological chemistry, 1990, 54(12): 3221-3226.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
535.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₈H₄₀O₆

[ Molecular Weight ]:
472.614

[ Flash Point ]:
291.8±26.6 °C

[ Exact Mass ]:
472.282501

[ PSA ]:
115.06000

[ LogP ]:
9.25

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.595

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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