Hydroxylapatite
Names
[ CAS No. ]:
1306-06-5
[ Name ]:
Hydroxylapatite
[Synonym ]:
Durapatite
Hydroxylapatite
Calcium phosphate hydroxide,Durapatite,Hydroxylapatite
Hydroxyapatite
Monite
MFCD00010904
Calcium hydroxide phosphate (5:1:3)
EINECS 215-145-7
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
3.140 g/cm3
[ Boiling Point ]:
158ºC at 760 mmHg
[ Melting Point ]:
1100 °C(lit.)
[ Molecular Formula ]:
Ca2HO5P
[ Molecular Weight ]:
502.311
[ Exact Mass ]:
501.675964
[ PSA ]:
119.12000
[ LogP ]:
0.20920
[ Storage condition ]:
−20°C
[ Water Solubility ]:
H2O: 0.3 mg/mL, clear, colorless
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MY8434000
- CHEMICAL NAME :
- Hydroxylapatite (Ca5(OH)(PO4)3) (9CI)
- CAS REGISTRY NUMBER :
- 1306-06-5
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- Ca5-H-O13-P3
- MOLECULAR WEIGHT :
- 502.32
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >25350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >19850 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >99500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >25500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >30 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 200 mg/L
- REFERENCE :
- IJBBBQ Indian Journal of Biochemistry and Biophysics. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.8- 1971- Volume(issue)/page/year: 19,71,1982
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
MY8434000
Articles
J. Appl. Microbiol. 117(6) , 1798-809, (2014)
To test the effect of 0·4% stannous fluoride (SnF2 ) glycerine-based gels on specific portions of the bacterial community in both a clinical observational study and in vitro multispecies plaque-derive...
Enhanced enterovirus 71 virus-like particle yield from a new baculovirus design.Biotechnol. Bioeng. 112 , 2005-15, (2015)
Enterovirus 71 (EV71) is responsible for the outbreaks of hand-foot-and-mouth disease in the Asia-Pacific region. To produce the virus-like particle (VLP) vaccine, we previously constructed recombinan...
Antibacterial and anti-biofilm activity of mouthrinses containing cetylpyridinium chloride and sodium fluoride.BMC Microbiol. 15 , 169, (2015)
Cetylpyridinium chloride (CPC) and sodium fluoride augment oral hygiene by inactivating bacteria and inhibiting enamel demineralisation, respectively. However, there are few reports in the literature ...