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(R,S)-MCPG sodium salt

Names

[ CAS No. ]:
1303994-09-3

[ Name ]:
(R,S)-MCPG sodium salt

[Synonym ]:
Benzeneacetic acid, α-amino-4-carboxy-α-methyl-, sodium salt (1:2)
Disodium 4-(1-amino-1-carboxylatoethyl)benzoate

Biological Activity

[Description]:

MCPG is a carboxylic phenyl glycine. MCPG can block metabotropic glutamate receptor (mGluR)(HY-15129) and has antagonistic activity of mGluR subtype. MCPG can be used to study the induction and maintenance of long-term potentiation (LTP) [1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR
Research Areas >> Neurological Disease

[References]

[1]. Riedel G, et al. Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG. J Neurosci. 1995 Jan;15(1 Pt 1):87-98.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H10NNaO4

[ Molecular Weight ]:
231.18

[ Exact Mass ]:
253.032700

Related Compounds