Amylmetacresol

Names

[ Name ]:
Amylmetacresol

[Synonym ]:
AMYL(6-)-M-CRESOL
Amyleine
5-Methyl-2-pentylphenol
5-METHYL-2-N-PENTYLPHENOL
6-n-pentyl-m-cresol
AMYL-M-CRESOL
3-Hydroxy-1-methyl-4-pentyl-benzol
6-pentyl-m-creso
5-Methyl-2-pentylphenol,Amylmetacresol
6-PENTYL-M-CRESOL
5-Methyl-2-pentyl-phenol
PENTYL-M-CRESOL
Amylmetacresol
6-n-amyl-m-cresol
6-AMYL-M-CRESOL

Biological Activity

[Description]:

Amylmetacresol is a local anesthetic and possesses antiviral (such HIV) effect. Amylmetacresol has the potential for the study in sore throat[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

Research Areas >> Neurological Disease

[References]

[1]. Martina Morokutti-Kurz, et al. Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat. Int J Gen Med. 2017 Feb 28;10:53-60.

Chemical & Physical Properties

[ Density]:
0.955g/cm3

[ Boiling Point ]:
273.2ºC at 760 mmHg

[ Melting Point ]:
24°C

[ Molecular Formula ]:
C₁₂H₁₈O

[ Molecular Weight ]:
178.27100

[ Flash Point ]:
125.3ºC

[ Exact Mass ]:
178.13600

[ PSA ]:
20.23000

[ LogP ]:
3.43330

[ Vapour Pressure ]:
0.00348mmHg at 25°C

[ Index of Refraction ]:
1.516

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Practically insoluble in water, very soluble in acetone and in ethanol (96 per cent).

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GP3100000

CHEMICAL NAME :: m-Cresol, 6-pentyl-

CAS REGISTRY NUMBER :: 1300-94-3

BEILSTEIN REFERENCE NO. :: 2440952

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H18-O

MOLECULAR WEIGHT :: 178.30

WISWESSER LINE NOTATION :: QR B5 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 32,592,1935

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
UN 3145 8/PG III

[ RTECS ]:
GP3100000

[ Packaging Group ]:
III

[ HS Code ]:
2907199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2907199090

[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%