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ZD 7114 hydrochloride

Names

[ CAS No. ]:
129689-28-7

[ Name ]:
ZD 7114 hydrochloride

[Synonym ]:
Acetamide,2-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethoxy]phenoxy]-N-(2-methoxyethyl)
(S)-2-(4-(2-((2-Hydroxy-3-phenoxypropyl)amino)ethoxy)phenoxy)-N-(2-methoxyethyl)acetamide hydrochloride
ZD 7114 hydrochloride
(S)-4-[2-(2-hydroxy-3-phenoxypropylamino)ethoxy]-N-(2-methoxyethyl)-phenoxyacetamide hydrochloride

Biological Activity

[Description]:

ZD-7114 hydrochloride is a potent and selective agonist of β3-adrenergic. ZD-7114 hydrochloride is a selective thermogenic agent in vivo. ZD-7114 hydrochloride can be used in study obesity and diabetes[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[References]

[1]. Howe, Ralph, et al. Selective .beta.3-adrenergic agonists of brown adipose tissue and thermogenesis. 2. [4-[2-[(2-Hydroxy-3-phenoxypropyl)amino]ethoxy]phenoxy]acetamides. Journal of Medicinal Chemistry, 35(10), 1759–1764.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H31ClN2O6

[ Molecular Weight ]:
454.94400

[ Exact Mass ]:
454.18700

[ PSA ]:
101.77000

[ LogP ]:
3.26950

MSDS

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Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ RIDADR ]:
UN 3077 9 / PGIII

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds