MIND4-19

Names

[ CAS No. ]:
129544-85-0

[ Name ]:
MIND4-19

Biological Activity

[Description]:

MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington's disease[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Sirtuin
Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin
Research Areas >> Neurological Disease

[Target]

SIRT2:7.0 μM (IC50)


[References]

[1]. Quinti L, et al. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models. Cell Chem Biol. 2016 Jul 21;23(7):849-861.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H19N3OS

[ Molecular Weight ]:
373.47

Related Compounds