(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin trifluoroacetate salt

Names

[ Name ]:
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin trifluoroacetate salt

[Synonym ]:
PHENYLAC-D-TYR(ET)-PHE-GLN-ASN-LYS-PRO-ARG-NH2
Phaa-D-Tyr(Et)-Phe-Gln-Asn-Lys-Pro-Arg-NH2

Biological Activity

[Description]:

(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin is a potent vasopressin V1 receptor (VP V1R) antagonist. (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin significantly decreases the mean arterial pressure (MAP) in rats[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Vasopressin Receptor

[References]

[1]. Levi DI, et al. High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons. Cell Rep. 2021 Mar 16;34(11):108866.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₄H₇₆N₁₄O₁₁

[ Molecular Weight ]:
1097.27000

[ Exact Mass ]:
1096.58000

[ PSA ]:
421.33000

[ LogP ]:
4.30690