β-Naphthoflavone-CH2-Br

Names

[ Name ]:
β-Naphthoflavone-CH2-Br

Biological Activity

[Description]:

β-Naphthoflavone-CH2-Br (β-NF-CH2-Br) is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br can be used to synthesize the PROTAC β-NF-JQ1(HY-130256)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[Target]

cIAP1

[References]

[1]. Ohoka N, et al. Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins. ACS Chem Biol. 2019 Oct 16.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₃BrO₂

[ Molecular Weight ]:
365.22

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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