Pregnanolone

Names

[ CAS No. ]:
128-20-1

[ Name ]:
Pregnanolone

[Synonym ]:
MFCD00067137
Pregnanolone II
5-Pregnan-3-ol-20-one
pregnanalone
Pregnan-20-one, 3-hydroxy-, (3α)-
PREGNAN-3A-OL-20-ONE
3alpha-hydroxy-5beta-pregnan-20-one
(3α)-3-Hydroxypregnan-20-one
Pregnan-20-one,3-hydroxy-, (3a,5b)-
Butabindide oxalate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
431.2±18.0 °C at 760 mmHg

[ Melting Point ]:
149ºC

[ Molecular Formula ]:
C₂₁H₃₄O₂

[ Molecular Weight ]:
318.493

[ Flash Point ]:
183.9±13.8 °C

[ Exact Mass ]:
318.255890

[ PSA ]:
37.30000

[ LogP ]:
4.89

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.524

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU4384000

CHEMICAL NAME :: 5-beta-Pregnan-20-one, 3-alpha-hydroxy-

CAS REGISTRY NUMBER :: 128-20-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C21-H34-O2

MOLECULAR WEIGHT :: 318.55

WISWESSER LINE NOTATION :: L E5 B666TJ A1 E1 FV1 OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 27500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,117,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 66 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,117,1968

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351

[ Precautionary Statements ]:
P281

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R40

[ Safety Phrases ]:
22-36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
TU4384000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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