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Chitohexaose hexahydrochloride

Names

[ CAS No. ]:
127171-88-4

[ Name ]:
Chitohexaose hexahydrochloride

Biological Activity

[Description]:

Chitohexaose hexahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitohexaose binds to the active sites of TLR4 and inhibits LPS induced inflammation[1][2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)
Research Areas >> Inflammation/Immunology

[References]

[1]. Qini Zhao, et al. Chitoheptaose Promotes Heart Rehabilitation in a Rat Myocarditis Model by Improving Antioxidant, Anti-Inflammatory, and Antiapoptotic Properties. Oxid Med Cell Longev. 2020 Apr 11;2020:2394704.

[2]. Santosh K Panda, et al. Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia. PLoS Pathog. 2012;8(5):e1002717.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H74Cl6N6O25

[ Molecular Weight ]:
1203.72

Related Compounds