Chloramine-T

Names

[ CAS No. ]:
127-65-1

[ Name ]:
Chloramine-T

[Synonym ]:
Euclorina
Chloramine (T)
CHLORAMINE-T-TRIHYDRATE
clorosan
CHLORAMINE-T, TRIHYDRATE OR - 250 G
Tosylchloramide sodium
MI 9
N-Chloro-4-toluenesulfonamide,sodium salt
NF X
Kloramin (VAN)
Sodium chloro[(4-methylphenyl)sulfonyl]azanide
MFCD00000522
Halamid
MeC6H4SO3NNaCl
Chloramine-T
MIANINE
Aktiven
N-CHLORO-4-TOLUOLSULFONAMID SODIUM
GANSIL
sodium N-chloro-p-toluenesulfonamide
Sodium chloro(tosyl)amide
Benzenesulfonamide, N-chloro-4-methyl-, sodium salt (1:1)
Chlorazene
CHLORAMINE T TRIHYDRATE
Clorina
Chloramine T
BENZENESULFONAMIDE,N-CHLORO-4-METHYL-, SODIUM SALT (1:1)
aktivin
anexol
EINECS 204-854-7

Biological Activity

[Description]:

Chloramine-T is a titrimetric reagent, and an oxidizing agent.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.36g/cm3

[ Boiling Point ]:
314.3ºC at 760mmHg

[ Melting Point ]:
167-170 °C(lit.)

[ Molecular Formula ]:
C₇H₇ClNNaO₂S

[ Molecular Weight ]:
227.644

[ Flash Point ]:
143.9ºC

[ Exact Mass ]:
226.978378

[ PSA ]:
42.52000

[ LogP ]:
3.29200

[ Stability ]:
Stable. Incompatible with strong oxidizing agents. May decompose violently if heated above 130 C. May decompose on exposure to air.

[ Water Solubility ]:
H2O: >100 mg/mL

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XT5616800

CHEMICAL NAME :: p-Toluenesulfonamide, N-chloro-, sodium salt

CAS REGISTRY NUMBER :: 127-65-1

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C7-H8-Cl-N-O2-S.Na

MOLECULAR WEIGHT :: 228.66

WISWESSER LINE NOTATION :: GMSWR DI &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - cyanosis

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - muscle weakness

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 100 ppm/24H

REFERENCE :: ARMCAH Annual Review of Medicine. (Annual Reviews, Inc., POB 10139, Palo Alto, CA 94303) V.1- 1950- Volume(issue)/page/year: 21,409,1970 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83916 No. of Facilities: 93 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 378 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83916 No. of Facilities: 190 (estimated) No. of Industries: 7 No. of Occupations: 8 No. of Employees: 1829 (estimated) No. of Female Employees: 1284 (estimated)

Safety Information

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R22;R31;R34;R42

[ Safety Phrases ]:
S22-S26-S36/37/39-S45-S7-S1/2

[ RIDADR ]:
UN 3263 8/PG 3

[ WGK Germany ]:
2

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%