NALTRINDOLE ISOTHIOCYANATE

Names

[ CAS No. ]:
126876-64-0

[ Name ]:
NALTRINDOLE ISOTHIOCYANATE

[Synonym ]:
naltrindole isothiocyanate

Chemical & Physical Properties

[ Density]:
1.68g/cm3

[ Boiling Point ]:
718.7ºC at 760mmHg

[ Molecular Formula ]:
C₂₇H₂₅N₃O₃S

[ Molecular Weight ]:
471.57100

[ Flash Point ]:
388.5ºC

[ Exact Mass ]:
471.16200

[ PSA ]:
113.17000

[ LogP ]:
4.24480

[ Vapour Pressure ]:
1.12E-21mmHg at 25°C

[ Index of Refraction ]:
1.882

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Alkylation of opioid receptors by 5'-naltrindole-isothiocyanate injected into the nucleus accumbens of rats: receptor selectivity and anatomical diffusion.

Synapse 60(5) , 384-91, (2006)

Subtypes of the delta opioid receptor (Oprd1) have been suggested based on pharmacology studies. However, these subtypes have not been confirmed biochemically using either receptor binding assays or m...

Microinjection of the delta-opioid receptor selective antagonist naltrindole 5'-isothiocyanate site specifically affects cocaine self-administration in rats responding under a progressive ratio schedule of reinforcement.

Behav. Brain Res. 182(1) , 140-4, (2007)

Whether the delta-opioid receptor (DOR) system can modulate behavioral effects of cocaine remains equivocal. We examined whether site- and subtype-selective blockade of DORs within the rat mesocortico...

Evidence for chemical differentiation of delta opioid receptor subtypes by the sulfhydryl reagent N-ethylmaleimide.

Receptor 4(2) , 81-91, (1994)

In this study, the delta receptor-selective nonequilibrium affinity ligands, 5'-NTII and DALCE, and the nonspecific sulfhydryl reagent NEM were evaluated over a range of concentrations and treatment c...