Metronidazole-d4 hydrochloride

Names

[ CAS No. ]:
1261397-74-3

[ Name ]:
Metronidazole-d4 hydrochloride

[Synonym ]:
1H-Imidazole-1-ethan-α,α,β,β-d4-ol, 2-methyl-5-nitro-, hydrochloride (1:1)
2-(2-Methyl-5-nitro-1H-imidazol-1-yl)(2H4)ethanol hydrochloride (1:1)

Biological Activity

[Description]:

Metronidazole-d4 hydrochloride is the deuterium labeled Metronidazole hydrochloride[1].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Molecular Formula ]:
C6H6D4ClN3O3

[ Molecular Weight ]:
211.639

[ Exact Mass ]:
211.066177

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351

[ Precautionary Statements ]:
P281

[ RIDADR ]:
NONH for all modes of transport

Related Compounds