bis-(4-dimethylamino-phenyl)-phenyl-d5-carbenium picrate

Names

[ CAS No. ]:
1258668-21-1

[ Name ]:
bis-(4-dimethylamino-phenyl)-phenyl-d5-carbenium picrate

[Synonym ]:
Malachite Green-d5 picrate
Bis-(4-dimethylaminophenyl)-phenyl-d5-carbenium picrate

Biological Activity

[Description]:

Malachite green-d5 (picrate) is the deuterium labeled Malachite green picrate[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Molecular Formula ]:
C29H22D5N5O7

[ Molecular Weight ]:
562.58500

[ Exact Mass ]:
562.22200

[ PSA ]:
166.77000

[ LogP ]:
7.51820

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H228-H301

[ Precautionary Statements ]:
P210-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
11-25

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2926 4.1/PG 3