fmoc-[15n]val-oh

Names

[ Name ]:
fmoc-[15n]val-oh

[Synonym ]:
MFCD00190536
L-Valine-15N,N-Fmoc derivative
Fmoc-Val-OH-15N

Biological Activity

[Description]:

Fmoc-L-Val-OH-15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-236.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-236.

Chemical & Physical Properties

[ Melting Point ]:
143-145ºC

[ Molecular Formula ]:
C₂₀H₂₁₁₅NO₄

[ Molecular Weight ]:
340.38

[ Exact Mass ]:
340.14400

[ PSA ]:
75.63000

[ LogP ]:
4.02520

[ Storage condition ]:
-15°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3