N-[(1S)-1-[[(6S)-6-[5-(7-BROMO-9,9-DIFLUORO-9H-FLUOREN-2-YL)-1H-IMIDAZOL-2-YL]-5-AZASPIRO[2.4]HEPT-5-YL]CARBONYL]-2-METHYLPROPYL]CARBAMIC ACID METHYL ESTER

Names

[ Name ]:
N-[(1S)-1-[[(6S)-6-[5-(7-BROMO-9,9-DIFLUORO-9H-FLUOREN-2-YL)-1H-IMIDAZOL-2-YL]-5-AZASPIRO[2.4]HEPT-5-YL]CARBONYL]-2-METHYLPROPYL]CARBAMIC ACID METHYL ESTER

[Synonym ]:
Ledipasvir acetone
Carbamic acid, N-[(1S)-1-[[(6S)-6-[5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl]carbonyl]-2-methylpropyl]-, methyl ester
(1-{6-[5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-aza-spiro[2.4]heptane-5-carbonyl}-2-methyl-propyl)carbamic acid methyl ester
Methyl [(2S)-1-{(6S)-6-[5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl}-3-methyl-1-oxo-2-butanyl]carbamate
Ledipasvir Intermediate 13

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
789.0±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₉H₂₉BrF₂N₄O₃

[ Molecular Weight ]:
599.466

[ Flash Point ]:
431.0±32.9 °C

[ Exact Mass ]:
598.139099

[ PSA ]:
87.32000

[ LogP ]:
5.36

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.660