(4R,4aR,7S,7aR,12bS)-9-ethoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol,hydrochloride

Names

[ CAS No. ]:
125-30-4

[ Name ]:
(4R,4aR,7S,7aR,12bS)-9-ethoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol,hydrochloride

[Synonym ]:
CODETHYLINE HYDROCHLORIDE
Ethylmorphinhydrochloriddihydrat
UNII-MFM5450P3T
Ethylmorphine HCl
3-O-Ethylmorphine hydrochloride
O-Ethylmorphine hydrochloride
Dionin hydrochloride
Ethylmorphine hydrochloride
Dionine hydrochloride
EINECS 204-734-4

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
472.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₉H₂₄ClNO₃

[ Molecular Weight ]:
349.85200

[ Flash Point ]:
239.4ºC

[ Exact Mass ]:
349.14400

[ PSA ]:
41.93000

[ LogP ]:
2.63110

[ Vapour Pressure ]:
1.01E-09mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD0874000

CHEMICAL NAME :: Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-3-ethoxy-17-methyl-, hydrochloride

CAS REGISTRY NUMBER :: 125-30-4

LAST UPDATED :: 199109

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C19-H23-N-O3.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,727,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 771 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 15,640,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 265 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 15,640,1957

Related Compounds

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