SSR-241586

Names

[ Name ]:
SSR-241586

Biological Activity

[Description]:

SSR-241586 is an antagonist of neurokinin receptors. SSR-241586 is shown to be active in the treatment of depression, schizophrenia, urinary trouble, emesis, and irritable bowel syndrome (IBS)[1][2].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor

[Target]

Neurokinin receptors[1]

[References]

[1]. Métro TX, et al. Asymmetric synthesis of an antagonist of neurokinin receptors: SSR 241586. J Org Chem. 2011 Apr 15;76(8):2594-602.

[2]. Cochi A, et al. Enantioselective synthesis of SSR 241586 by using an organo-catalyzed Henry reaction. Org Lett. 2010 Aug 20;12(16):3693-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₄₂Cl₂N₄O₃

[ Molecular Weight ]:
601.61

Related Compounds

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