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Lalistat 2

Names

[ CAS No. ]:
1234569-09-5

[ Name ]:
Lalistat 2

[Synonym ]:
MFCD31544494
4-(1-Piperidinyl)-1,2,5-thiadiazol-3-yl 1-piperidinecarboxylate
1-Piperidinecarboxylic acid 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester
1-Piperidinecarboxylic acid, 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester
Lalistat-2
Lalistat 2

Biological Activity

[Description]:

Lalistat 2 is a specific inhibitor of lysosomal acid lipase (LAL) with no effect on other forms of lipase[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Hamilton J, et al. A new method for the measurement of lysosomal acid lipase in dried blood spots using the inhibitor Lalistat 2. Clin Chim Acta. 2012;413(15-16):1207-1210.

[2]. Lukacs Z, et al. Best practice in the measurement and interpretation of lysosomal acid lipase in dried blood spots using the inhibitor Lalistat 2. Clin Chim Acta. 2017;471:201-205.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
438.5±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H20N4O2S

[ Molecular Weight ]:
296.388

[ Flash Point ]:
219.0±28.7 °C

[ Exact Mass ]:
296.130707

[ LogP ]:
3.29

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.586

Related Compounds

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