Pefloxacin-D5

Names

[ CAS No. ]:
1228182-51-1

[ Name ]:
Pefloxacin-D5

[Synonym ]:
Pefloxacine-d5
1-Ethyl-d5-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Pefloxacin-d5

Biological Activity

[Description]:

Pefloxacin-d5 is the deuterium labeled 4-Nitrobenzonitrile[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H15D5FN3O3

[ Molecular Weight ]:
338.39

[ Exact Mass ]:
338.18000

[ PSA ]:
65.78000

[ LogP ]:
1.61340

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-52

[ RIDADR ]:
NONH for all modes of transport

Related Compounds