L-Lysine-1,2,3,4,5,6(hydrochloride (1:1))-13C6

Names

[ CAS No. ]:
1228077-86-8

[ Name ]:
L-Lysine-1,2,3,4,5,6(hydrochloride (1:1))-13C6

Biological Activity

[Description]:

L-Lysine-1,2,3,4,5,6(hydrochloride (1:1))-13C6 is the 13C labeled L-Lysine hydrochloride[1]. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health[2][3][4].

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Al-Malki AL, et al. Suppression of acute pancreatitis by L-lysinein mice. BMC Complement Altern Med. 2015 Jun 23;15:193.  

[3]. Baruffol C, et al. L-lysine dose dependently delays gastric emptying and increases intestinal fluid volume in humans and rats. Neurogastroenterol Motil. 2014 Jul26(7):999-1009.  

[4]. Shimomura A, et al. Dietary L-lysineprevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep25(9):1954-65.  

Chemical & Physical Properties

[ Melting Point ]:
263-264 °C (dec.) (lit.)

[ Molecular Formula ]:
C6H15ClN2O2

[ Molecular Weight ]:
188.7

Safety Information

[ WGK Germany ]:
3

Related Compounds