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SB 258585 hydrochloride

Names

[ CAS No. ]:
1216468-02-8

[ Name ]:
SB 258585 hydrochloride

[Synonym ]:
Benzenesulfonamide, 4-iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-, hydrochloride (1:1)
4-Iodo-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]benzenesulfonamide hydrochloride (1:1)
MFCD06798382
4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide hydrochloride (1:1)

Biological Activity

[Description]:

SB-258585 is a high affinity ligand for the 5-HT6 receptor. SB-258585 binds highly to a single receptor population in a human cell line that recombines 5-HT6 receptors. SB-258585 can be used to label recombinant and natural 5-HT6 receptor [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Hirst WD, et al. Characterization of [(125)I]-SB-258585 binding to human recombinant and native 5-HT(6) receptors in rat, pig and human brain tissue. Br J Pharmacol. 2000 Aug;130(7):1597-605.  

Chemical & Physical Properties

[ Molecular Formula ]:
C18H23ClIN3O3S

[ Molecular Weight ]:
523.82

[ Exact Mass ]:
523.019348

[ Appearance of Characters ]:
SB 258585 hydrochloride

[ Storage condition ]:
store at -20℃ for one year（Powder）

Related Compounds