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GR 144053 trihydrochloride

Names

[ CAS No. ]:
1215333-48-4

[ Name ]:
GR 144053 trihydrochloride

[Synonym ]:
{4-[4-(4-Carbamimidoylphenyl)-1-piperazinyl]-1-piperidinyl}acetic acid trihydrochloride
{4-[4-(4-Carbamimidoylphenyl)piperazin-1-yl]piperidin-1-yl}acetic acid trihydrochloride
1-Piperidineacetic acid, 4-[4-[4-(aminoiminomethyl)phenyl]-1-piperazinyl]-, hydrochloride (1:3)

Biological Activity

[Description]:

GR 144053 trihydrochloride is a selective and non-peptic GPIIb/IIIa inhibitor (IC50=37 nM)[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Cytoskeleton >> Integrin

[References]

[1]. Uhl B, et al. Vitronectin promotes immunothrombotic dysregulation in the venular microvasculature. Front Immunol. 2023 Feb 8;14:1078005.  

Chemical & Physical Properties

[ Molecular Formula ]:
C18H30Cl3N5O2

[ Molecular Weight ]:
454.82

[ Exact Mass ]:
453.146515

Related Compounds