cis-4,7,10,13,16,19-Docosahexaenoic-21,21,22,22,22-d5 acid

Names

[ CAS No. ]:
1197205-71-2

[ Name ]:
cis-4,7,10,13,16,19-Docosahexaenoic-21,21,22,22,22-d5 acid

[Synonym ]:
(4Z,7Z,10Z,13Z,16Z,19Z)-(21,21,22,22,22-H)-4,7,10,13,16,19-Docosahexaenoic acid
4,7,10,13,16,19-Docosahexaenoic-21,21,22,22,22-d acid, (4Z,7Z,10Z,13Z,16Z,19Z)-
21,21,22,22,22-pentadeuteriodocosa-4,7,10,13,16,19-hexaenoic acid

Biological Activity

[Description]:

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
446.7±24.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₂H₂₇D₅O₂

[ Molecular Weight ]:
333.52

[ Flash Point ]:
343.4±18.0 °C

[ Exact Mass ]:
333.271606

[ PSA ]:
37.30000

[ LogP ]:
6.78

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.521

[ Storage condition ]:
-20°C

[ Stability ]:
Light and Air Sensitive

Safety Information

[ RIDADR ]:
NA 1993 / PGIII

Articles

Chiral chromatography-tandem mass spectrometry applied to the determination of pro-resolving lipid mediators.

J. Chromatogr. A. 1360 , 150-63, (2014)

Pro-resolving lipid mediators are a class of endogenously synthesized molecules derived from different fatty acids, such as arachidonic, docosahexaenoic or eicosapentaenoic acid, which are derived int...

Serum levels of lipid metabolites in age-related macular degeneration.

FASEB J. 29 , 4579-88, (2015)

Age-related macular degeneration (AMD) is a neurodegenerative disease that causes adult-onset blindness. There are 2 forms of this progressive disease: wet and dry. Currently there is no cure for AMD,...

Neuroprotectin/protectin D1: endogenous biosynthesis and actions on diabetic macrophages in promoting wound healing and innervation impaired by diabetes.

Am. J. Physiol. Cell Physiol. 307(11) , C1058-67, (2014)

Dysfunction of macrophages (MΦs) in diabetic wounds impairs the healing. MΦs produce anti-inflammatory and pro-resolving neuroprotectin/protectin D1 (NPD1/PD1, 10R,17S-dihydroxy-docosa-4Z,7Z,11E,13E,1...