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2-Furanmethanaminium,N,N,N,5-tetramethyl-, iodide (1:1)

Names

[ CAS No. ]:
1197-60-0

[ Name ]:
2-Furanmethanaminium,N,N,N,5-tetramethyl-, iodide (1:1)

[Synonym ]:
methylfurmethide
5-Methylfurfuryltrimethylammonium iodide
Methylfurmetide
5 MFT
5-Methylfurtrethonium iodide
Preparation 7070
5-Methylfurmithide
Methylfurmethide iodide

Biological Activity

[Description]:

Methylfurmethide is an acetylcholine receptor. Methylfurmethide blocks the uptake of atropine. Methylfurmethide can be used to study the properties of acetylcholine receptors in intestinal smooth muscle [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. PATON WD, et al. THE UPTAKE OF ATROPINE AND RELATED DRUGS BY INTESTINAL SMOOTH MUSCLE OF THE GUINEA-PIG IN RELATION TO ACETYLCHOLINE RECEPTORS. Proc R Soc Lond B Biol Sci. 1965 Aug 24;163:1-44.  

Chemical & Physical Properties

[ Molecular Formula ]:
C9H16INO

[ Molecular Weight ]:
281.13

[ Exact Mass ]:
281.02800

[ PSA ]:
13.14000

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BR7980000
CHEMICAL NAME :
Ammonium, (5-methylfurfuryl)trimethyl-, iodide
CAS REGISTRY NUMBER :
1197-60-0
LAST UPDATED :
199206
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H16-N-O.I
MOLECULAR WEIGHT :
281.16
WISWESSER LINE NOTATION :
T5OJ B1K1&1&1 E1 &I

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
33 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 7,130,1952
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3795 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Kidney, Ureter, Bladder - incontinence
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,184,1976

Safety Information

[ HS Code ]:
2932190090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%