Fmoc-Asp-OH

Names

[ CAS No. ]:
119062-05-4

[ Name ]:
Fmoc-Asp-OH

[Synonym ]:
Fmoc-Asp-OH
L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartic acid
N-Fmoc-L-aspartic acid
MFCD00237654
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}succinic acid
Fmoc-L-aspartic acid

Biological Activity

[Description]:

(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-aspartic acid is an aspartic acid derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
587.2±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₇NO₆

[ Molecular Weight ]:
355.341

[ Flash Point ]:
308.9±28.7 °C

[ Exact Mass ]:
355.105591

[ PSA ]:
112.93000

[ LogP ]:
3.55

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.628

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Synthesis of N-linked glycopeptides via solid-phase aspartylation.

Org. Biomol. Chem. 8 , 3723-3733, (2010)

An efficient strategy for the preparation of N-linked glycopeptides is described. The method relies on the use of side chain protecting groups on aspartic acid residues, namely the allyl and Dmab este...

The aspartimide problem in Fmoc-based SPPS. Part I.

J. Pept. Sci. 9 , 36-46, (2003)

A variety of Asp beta-carboxy protecting groups, Hmb backbone protection and a range of Fmoc cleavage protocols have been employed in syntheses of the model hexapeptide H-VKDGYI-OH to investigate the ...

The aspartimide problem in Fmoc-based SPPS. Part II.

J. Pept. Sci. 9 , 518-526, (2003)

The sequence dependence of base-catalysed aspartmide formation during Fmoc-based SPPS was systematically studied employing the peptide models H-Val-Lys-Asp-Xaa-Tyr-Ile-OH. The extent of formation of a...