N-Acetyl-L-glutamic acid
Names
[ CAS No. ]:
1188-37-0
[ Name ]:
N-Acetyl-L-glutamic acid
[Synonym ]:
(2S)-2-(acetylamino)pentanedioic acid
EINECS 214-708-4
N-Acetyl-L-glutamicacid
AC-GLU-OH
N-acetyl-L-glutamate
(S)-2-acetamidopentanedioic acid
N-ACETYL-L-GLU
N-AC-L-GLU
MFCD00002802
N-Acetyl-L-Glutamic
N-Acetyl-L-glutamic Acid
N-acetyl-Glu
acetylglutamicacid
Acetyl-L-glutamic acid
2-(acetylamino)pentanedioic acid
L-Glutamic acid, N-acetyl-
NAcGlu
n-acetylglutamic
N-Acetylglutamate
n-acetylglutamicacid
l-glutamicaci
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
495.9±35.0 °C at 760 mmHg
[ Melting Point ]:
194-196 °C(lit.)
[ Molecular Formula ]:
C7H11NO5
[ Molecular Weight ]:
189.166
[ Flash Point ]:
253.7±25.9 °C
[ Exact Mass ]:
189.063721
[ PSA ]:
103.70000
[ LogP ]:
-2.24
[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C
[ Index of Refraction ]:
1.502
[ Storage condition ]:
2~8°C
[ Water Solubility ]:
2.7 g/100 mL (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LZ9725000
- CHEMICAL NAME :
- L-Glutamic acid, N-acetyl-
- CAS REGISTRY NUMBER :
- 1188-37-0
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C7-H11-N-O5
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >7 gm/kg
- TOXIC EFFECTS :
- Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),36,1995
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6838 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),36,1995
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 711 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),36,1995
Safety Information
[ Hazard Codes ]:
Xi
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
LZ9725000
[ HS Code ]:
29241900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Nature 457(7231) , 910-4, (2009)
Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...
Highly sensitive GC/MS/MS method for quantitation of amino and nonamino organic acids.Anal. Chem. 83(7) , 2705-11, (2011)
Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few inter...
Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.Clin. Biochem. 38(11) , 997-1008, (2005)
To set up a novel simple, sensitive, and reliable ion-pairing HPLC method for the synchronous separation of several purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemi...