EMD638683 (R-Form)

Names

[ CAS No. ]:
1184940-47-3

[ Name ]:
EMD638683 (R-Form)

[Synonym ]:
EMD638683 (R-Form)

Biological Activity

[Description]:

EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> SGK

Research Areas >> Metabolic Disease

[Target]

SGK1[1]

[References]

[1]. Ackermann TF, et al. EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem. 2011;28(1):137-46.

[Related Small Molecules]

EMD638683 | GSK 650394 | SGK1-IN-1

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₈F₂N₂O₄

[ Molecular Weight ]:
364.34300

[ Exact Mass ]:
364.12300

[ PSA ]:
102.15000

[ LogP ]:
3.26700

[ Storage condition ]:
2-8℃

Related Compounds

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