4,4'-Methylenebis(2,6-di-tert-butylphenol)
Names
[ CAS No. ]:
118-82-1
[ Name ]:
4,4'-Methylenebis(2,6-di-tert-butylphenol)
[Synonym ]:
Bis(3,5-di-tert-butyl-4-hydroxyphenyl)methane
4,4'-Methylenebis[2,6-bis(2-methyl-2-propanyl)phenol]
4,4'-methanediylbis(2,6-di-tert-butylphenol)
MFCD00008822
Phenol, 4,4'-methylenebis[2,6-bis(1,1-dimethylethyl)-
Ethanox 702
3,3',5,5'-Tetra-tert-butyl-4,4'-dihydroxydiphenylmethane
Phenol, 4,4'-methylenebis[2,6-di-tert-butyl-
4,4'-Methylenebis(2,6-di-tert-butylphenol)
EINECS 204-279-1
2,6-ditert-butyl-4-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]phenol
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
459.5±40.0 °C at 760 mmHg
[ Melting Point ]:
155-159 °C(lit.)
[ Molecular Formula ]:
C29H44O2
[ Molecular Weight ]:
424.659
[ Flash Point ]:
178.1±21.9 °C
[ Exact Mass ]:
424.334137
[ PSA ]:
40.46000
[ LogP ]:
9.49
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.527
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SL9650000
- CHEMICAL NAME :
- Phenol, 4,4'-methylenebis(2,6-bis(1,1-dimethylethyl)-
- CAS REGISTRY NUMBER :
- 118-82-1
- BEILSTEIN REFERENCE NO. :
- 1916919
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C29-H44-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2021 mg/kg/1W-C
- TOXIC EFFECTS :
- Liver - other changes Blood - other changes Biochemical - Metabolism (Intermediary) - lipids including transport
- REFERENCE :
- TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 8,77,1981
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 56700 mg/kg/2Y-C
- TOXIC EFFECTS :
- Gastrointestinal - ulceration or bleeding from large intestine Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring) Related to Chronic Data - death
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536073 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83032 No. of Facilities: 7725 (estimated) No. of Industries: 96 No. of Occupations: 64 No. of Employees: 120009 (estimated) No. of Female Employees: 20306 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
SL9650000
[ HS Code ]:
2907299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2907299090
[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%
Articles
Toxicol. Lett. 8(1-2) , 77-86, (1981)
Hepatic lipids were studied in Sprague-Dawley male rats given, 2,2'-methylenebis(4-ethyl-6-tert-butylphenol), 2,2'-methylenebis(4-methyl-6-tert-butylphenol), 4,4'-butylidenebis(3-methyl-6-tert-butylph...