6,7-dimethoxy-2-(2-(4-methoxyphenyl)ethyl)chromone

Names

[ Name ]:
6,7-dimethoxy-2-(2-(4-methoxyphenyl)ethyl)chromone

[Synonym ]:
dmpec

Biological Activity

[Description]:

NF-κB-IN-13 (compound 12) can significantly inhibit LPS-induced NF-κB activation and NO production in RAW264.7 macrophages. NF-κB-IN-13 has anti-inflammatory effects[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

NF-κB

[References]

[1]. Sin-Ling Wang, et al. 2-(2-Phenylethyl)-4H-chromen-4-one Derivatives from the Resinous Wood of Aquilaria sinensis with Anti-Inflammatory Effects in LPS-Induced Macrophages. Molecules. 2018 Jan 30;23(2):289.

Chemical & Physical Properties

[ Density]:
1.192g/cm3

[ Boiling Point ]:
511.3ºC at 760mmHg

[ Molecular Formula ]:
C₂₀H₂₀O₅

[ Molecular Weight ]:
340.37

[ Flash Point ]:
225.1ºC

[ Exact Mass ]:
340.13100

[ PSA ]:
57.90000

[ LogP ]:
3.60400

[ Vapour Pressure ]:
1.44E-10mmHg at 25°C

[ Index of Refraction ]:
1.569

Related Compounds

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