Leuco Gentian Violet-d6

Names

[ CAS No. ]:
1173023-92-1

[ Name ]:
Leuco Gentian Violet-d6

[Synonym ]:
Bis(4-dimethylaminophenyl)-4-dimethylamino-d6-phenylmethane
Leucocrystal Violet-d6
Leucomethyl Green-d6
Leuco Gentian Violet-d6
Leuco Basic Violet 3-d6

Biological Activity

[Description]:

Leucocrystal violet-d6 is the deuterium labeled Leucocrystal violet[1]. Leucocrystal violet is a triphenylmethane dye which can be used to detect antimony in environmental and biological samples using spectrophotometric techniques[2][3].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Wu J, et al. Biodegradation of leuco derivatives of triphenylmethane dyes by Sphingomonas sp. CM9. Biodegradation. 2011 Sep;22(5):897-904.  

[3]. Tiwari KK, et al. A simple and sensitive analytical method for the determination of antimony in environmental and biological samples. Anal Sci. 2006 Feb22(2):259-62.  

Chemical & Physical Properties

[ Molecular Formula ]:
C25H25D6N3

[ Molecular Weight ]:
379.57100

[ Exact Mass ]:
379.28900

[ PSA ]:
9.72000

[ LogP ]:
5.06480

MSDS

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Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds