Propiophenone, 3-piperidino-4'-propoxy-, hydrochloride
Names
[ CAS No. ]:
1155-49-3
[ Name ]:
Propiophenone, 3-piperidino-4'-propoxy-, hydrochloride
[Synonym ]:
3-piperidin-1-yl-1-(4-propoxyphenyl)propan-1-one,hydrochloride
Chemical & Physical Properties
[ Density]:
1.027g/cm3
[ Boiling Point ]:
411.4ºC at 760mmHg
[ Molecular Formula ]:
C17H26ClNO2
[ Molecular Weight ]:
311.84700
[ Flash Point ]:
202.6ºC
[ Exact Mass ]:
311.16500
[ PSA ]:
29.54000
[ LogP ]:
4.27400
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UH4420000
- CHEMICAL NAME :
- Propiophenone, 3-piperidino-4'-propoxy-, hydrochloride
- CAS REGISTRY NUMBER :
- 1155-49-3
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C17-H25-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 311.89
- WISWESSER LINE NOTATION :
- T6NTJ A2VR DO3 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 31,21,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 57 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,559,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia Behavioral - muscle contraction or spasticity Behavioral - irritability
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 115,419,1955