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Butyrolactone V

Names

[ CAS No. ]:
1151509-01-1

[ Name ]:
Butyrolactone V

[Synonym ]:
Methyl (2R)-4-hydroxy-2-{[(3S)-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-6-yl]methyl}-3-(4-hydroxyphenyl)-5-oxo-2,5-dihydro-2-furancarboxylate
2-Furancarboxylic acid, 2-[[(3S)-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl]methyl]-2,5-dihydro-4-hydroxy-3-(4-hydroxyphenyl)-5-oxo-, methyl ester, (2R)-
Butyrolactone V

Biological Activity

[Description]:

Butyrolactone V is a butanolide compound. Butyrolactone V shows antiplasmodial activity against Plasmodium falciparum K1 with an IC50 of 7.9 µg/ml[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[References]

[1]. Haritakun R, et al. Butyrolactones from the fungus Aspergillus terreus BCC 4651. Chem Pharm Bull (Tokyo). 2010;58(11):1545-1548.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
680.8±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H24O8

[ Molecular Weight ]:
440.443

[ Flash Point ]:
235.6±25.0 °C

[ Exact Mass ]:
440.147125

[ LogP ]:
3.24

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.638

Related Compounds