H4R antagonist 2

Names

[ Name ]:
H4R antagonist 2

[Synonym ]:
Benzoic acid,3-fluoro-4-(4-methoxy-4-oxobutoxy)
4-[3-(methoxycarbonyl)propoxy]-3-fluorobenzoic acid
4-[3-(methylamino)azetidin-1-yl]-7,8-dihydro-6H-cyclopenta[4,5]furo[3,2-d]pyrimidin-2-amine

Biological Activity

[Description]:

H4R antagonist 2 (page 68), a Furo[3,2-d]pyrimidine derivative, is a potent H4R antagonist. H4R antagonist 2 can be used in research of rheumatoid arthritis[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

[References]

[1]. Elena CG, et, al. Furo[3,2-d]pyrimidine derivatives. WO2009056551A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₁₇N₅O

[ Molecular Weight ]:
259.31

[ Exact Mass ]:
259.14300

[ PSA ]:
80.94000

[ LogP ]:
1.08770

Related Compounds

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