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EPI-589

Names

[ CAS No. ]:
1147883-03-1

[ Name ]:
EPI-589

Biological Activity

[Description]:

EPI-589, a quinone derivative, is a safe and well tolerated oxidoreductase enzyme inhibitor. EPI-589 has the potential for the treatment of amyotrophic lateral sclerosis (ALS)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[Target]

IC50: oxidoreductase enzyme[1]


[In Vivo]

EPI-589 exhibits a significant improvement in cerebrospinal fluid (CSF) and plasma-based biomarkers known to be associated with neuroinflammation and ALS disease progression[2].

[References]

[1]. BioElectron’s EPI-589 Shows Positive Results in ALS Patients in Phase 2a Trial

[2]. Phase IIa trial of EPI-589 in ALS shows improvement in CSF

Chemical & Physical Properties

[ Molecular Formula ]:
C14H19NO4

[ Molecular Weight ]:
265.30

Related Compounds