<Suppliers Price>

Gramicidin S

Names

[ CAS No. ]:
113-73-5

[ Name ]:
Gramicidin S

[Synonym ]:
5H,22H-dipyrrolo[1,2-a:1',2'-p][1,4,7,10,13,16,19,22,25,28]decaazacyclotriacontine-5,22-dione, 12,29-bis(3-aminopropyl)-1,2,3,6,9,12,15,17a,18,19,20,23,26,29,32,34a-hexadecahydro-8,11,14,17,25,28,31,34-octahydroxy-15,32-bis(1-methylethyl)-9,26-bis(2-methylpropyl)-6,23-bis(phenylmethyl)-, (6R,7E,9S,10E,12S,13E,15S,16E,17aS,23R,24E,26S,27E,29S,30E,32S,33E,34aS)-
Gramicidin C
Cyclo(L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl)
Gramacidine S [INN-French]
Gramicin S 1
Gramicidinum S [INN-Latin]
Gramicidina S [INN-Spanish]
gramicidin s
Gramicin S-A

Biological Activity

[Description]:

Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic. Gramicidin S is active against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial membranes. Gramicidin S also inhibits cytochrome bd quinol oxidase[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Mogi T, et al. Gramicidin S and polymyxins: the revival of cationic cyclic peptide antibiotics. Cell Mol Life Sci. 2009 Dec;66(23):3821-6.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
1394.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C60H92N12O10

[ Molecular Weight ]:
1141.447

[ Flash Point ]:
797.4±34.3 °C

[ Exact Mass ]:
1140.705933

[ PSA ]:
353.38000

[ LogP ]:
0.10

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.596

Related Compounds