trans-3,4-Difluorocinnamic acid

Names

[ Name ]:
trans-3,4-Difluorocinnamic acid

[Synonym ]:
(2E)-3-(3,4-Difluorophenyl)-2-propenoic acid
trans-3,4-Difluorocinnamicacid
RARECHEM BK HW 0122
2-Propenoic acid, 3-(3,4-difluorophenyl)-, (2E)-
trans-3,4-Difluorociamic acid
trans-3-(3,4-Difluorophenyl)acrylic Acid
(E)-3-(3,4-Difluorophenyl)acrylic acid
(2E)-3-(3,4-Difluorophenyl)acrylic acid
QV1U1R CF DF &&trans or E Form
3,4-DIFLUOROCINNAMIC ACID
MFCD00010320

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
281.3±25.0 °C at 760 mmHg

[ Melting Point ]:
194-196 °C(lit.)

[ Molecular Formula ]:
C₉H₆F₂O₂

[ Molecular Weight ]:
184.139

[ Flash Point ]:
124.0±23.2 °C

[ Exact Mass ]:
184.033585

[ PSA ]:
37.30000

[ LogP ]:
2.45

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.569

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Room temperature copper(II)-catalyzed oxidative cyclization of enamides to 2,5-disubstituted oxazoles via vinylic C-H functionalization.

J. Org. Chem. 77(17) , 7526-37, (2012)

A copper(II)-catalyzed oxidative cyclization of enamides to oxazoles via vinylic C-H bond functionalization at room temperature is described. Various 2,5-disubstituted oxazoles bearing aryl, vinyl, al...