Doxazosin D8

Names

[ CAS No. ]:
1126848-44-9

[ Name ]:
Doxazosin D8

Biological Activity

[Description]:

Doxazosin D8 (UK 33274 D8) is a deuterium labeled Doxazosin (UK 33274). Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1 adrenergic receptors[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Research Areas >> Endocrinology
Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[References]

[1]. Miura, Y. and K. Yoshinaga, Doxazosin: a newly developed, selective alpha 1-inhibitor in the management of patients with pheochromocytoma. Am Heart J, 1988. 116(6 Pt 2): p. 1785-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H17D8N5O5

[ Molecular Weight ]:
459.52400

[ Exact Mass ]:
459.23600

[ PSA ]:
112.27000

[ LogP ]:
2.30190

Related Compounds