2-Methyl-2’-deoxyadenosine

Names

[ Name ]:
2-Methyl-2’-deoxyadenosine

[Synonym ]:
(2R,3S,5R)-5-(6-Amino-2-methyl-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol

Biological Activity

[Description]:

2-Methyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₅N₅O₃

[ Molecular Weight ]:
265.27

[ Exact Mass ]:
265.11700

[ PSA ]:
119.31000