Ilexsaponin B2

Names

[ Name ]:
Ilexsaponin B2

Biological Activity

[Description]:

Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

[Target]

PDE5:48.8 μM (IC50)

PDEI:477.5 μM (IC50)

[References]

[1]. Zichen Liu, et al. Rapid Screening of Potential Phosphodiesterase Inhibitors From the Roots of Ilex pubescens Hook. Et Arn. Using a Combination of Ultrafiltration and LC-MS. Evid Based Complement Alternat Med. 2017;2017:2749643.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₇H₇₆O₁₇

[ Molecular Weight ]:
913.09600

[ Exact Mass ]:
912.50800

[ PSA ]:
274.75000

[ LogP ]:
1.34370

[ Storage condition ]:
2-8℃

Ilexsaponin B2

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds