PC-766B

Names

[ Name ]:
PC-766B

[Synonym ]:
pc 766b

Biological Activity

[Description]:

PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase[1][2].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo). 1993 Jun;46(6):972-8.

[2]. Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation. J Antibiot (Tokyo). 1993 Jul;46(7):1139-44.

Chemical & Physical Properties

[ Density]:
1.17g/cm3

[ Boiling Point ]:
884.3ºC at 760mmHg

[ Molecular Formula ]:
C₄₃H₆₈O₁₂

[ Molecular Weight ]:
776.99

[ Flash Point ]:
255.2ºC

[ Exact Mass ]:
776.47100

[ PSA ]:
173.60000

[ LogP ]:
5.05000

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.555

Related Compounds

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