h-pro-pna tfa

Names

[ CAS No. ]:
108321-19-3

[ Name ]:
h-pro-pna tfa

[Synonym ]:
N-(4-Nitrophenyl)pyrrolidine-2-carboxamide P-pNA Pro-pNA
L-proline-p-nitroanilide
AmbscPOD_44/0762

Biological Activity

[Description]:

L-Proline p-nitroanilide (P-pNA) TFA is aproline derivatives.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Cathal S Mahon, et al. Characterization of a multimeric, eukaryotic prolyl aminopeptidase: an inducible and highly specific intracellular peptidase from the non-pathogenic fungus Talaromyces emersonii. Microbiology (Reading). 2009, 155.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₁₄F₃N₃O₅

[ Molecular Weight ]:
349.26

[ Exact Mass ]:
349.08900

[ PSA ]:
124.25000

[ LogP ]:
2.84360

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Generation of food-grade recombinant Lactobacillus casei delivering Myxococcus xanthus prolyl endopeptidase.

Appl. Microbiol. Biotechnol. 98(15) , 6689-700, (2014)

Prolyl endopeptidases (PEP) (EC 3.4.21.26), a family of serine proteases with the ability to hydrolyze the peptide bond on the carboxyl side of an internal proline residue, are able to degrade immunot...

Synthesis and biological evaluation of nigranoic acid esters as novel human neutrophil elastase inhibitors.

Nat. Prod. Res. 29 , 1650-6, (2015)

Human neutrophil elastase (HNE) has been implicated as a major contributor in the pathogenesis of diseases, such as lung disorders and other inflammatory diseases. A series of 12 new nigranoic acid es...

Characterization of a multimeric, eukaryotic prolyl aminopeptidase: an inducible and highly specific intracellular peptidase from the non-pathogenic fungus Talaromyces emersonii.

Microbiology 155 , 3673-3682, (2009)

Fungi are capable of degrading proteins in their environment by secreting peptidases. However, the link between extracellular digestion and intracellular proteolysis has scarcely been investigated. My...