Myricananin A

Names

[ Name ]:
Myricananin A

[Synonym ]:
Tricyclo[12.3.1.1]nonadeca-1(18),2,4,6(19),14,16-hexaene-3,8,9,17-tetrol, 16-methoxy-, (8S,9S)-
(8S,9S)-16-Methoxytricyclo[12.3.1.1]nonadeca-1(18),2(19),3,5,14,16-hexaene-3,8,9,17-tetrol

Biological Activity

[Description]:

Myricananin A is a colorless needle that has inhibitory effect on iNOS[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

Research Areas >> Inflammation/Immunology

[In Vitro]

Myricananin A (0-100 µM；24 h) 以剂量依赖性方式抑制 LPS 激活的巨噬细胞中 iNOS 的表达[1]。 Western Blot Analysis[1] Cell Line: LPS-activated macrophages. Concentration: 0, 1, 3, 10, 30 and 100 µM. Incubation Time: 24 h. Result: Inhibited the expression of iNOS.

[References]

[1]. Wang J, et al. Cyclic diarylheptanoids from Myrica nana inhibiting nitric oxide release. Bioorg Med Chem. 2008 Sep 15;16(18):8510-5.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
596.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₄O₅

[ Molecular Weight ]:
344.402

[ Flash Point ]:
314.7±30.1 °C

[ Exact Mass ]:
344.162384

[ PSA ]:
90.15000

[ LogP ]:
2.99

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.623

Related Compounds

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