5-fluoro-2',3'-dideoxycytidine

Names

[ Name ]:
5-fluoro-2',3'-dideoxycytidine

[Synonym ]:
5-Fluoro-2',3'-dideoxycytidine
5-F-ddC
D-FddC
Cytidine,2',3'-dideoxy-5-fluoro
2',3'-dideoxy-5-fluorocytidine

Biological Activity

[Description]:

2’,3’-Dideoxy-5-fluorocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.67g/cm3

[ Boiling Point ]:
386.2ºC at 760mmHg

[ Molecular Formula ]:
C₉H₁₂FN₃O₃

[ Molecular Weight ]:
229.21

[ Flash Point ]:
187.4ºC

[ Exact Mass ]:
229.08600

[ PSA ]:
91.36000

[ Vapour Pressure ]:
1.47E-07mmHg at 25°C

[ Index of Refraction ]:
1.665

5-fluoro-2',3'-dideoxycytidine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds