Crotonic acid
Names
[ CAS No. ]:
107-93-7
[ Name ]:
Crotonic acid
[Synonym ]:
Crotonic acid
(E)-But-2-enoic acid
MFCD00002701
α-Crotonic acid
2-Butenoic acid, (2E)-
(2E)-2-Butenoic acid
(2E)-But-2-enoic acid
trans-2-Butenoic acid
crotonate
EINECS 203-533-9
β-Methylacrylic acid
Chemical & Physical Properties
[ Density]:
1.027
[ Boiling Point ]:
185-199 ºC
[ Melting Point ]:
70-73ºC
[ Molecular Formula ]:
C4H6O2
[ Molecular Weight ]:
86.089
[ Flash Point ]:
88 ºC
[ Exact Mass ]:
86.036781
[ PSA ]:
37.30000
[ LogP ]:
0.80
[ Vapour density ]:
2.97 (vs air)
[ Vapour Pressure ]:
0.5±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.449
[ Water Solubility ]:
94 g/L (25 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GQ2900000
- CHEMICAL NAME :
- Crotonic acid, (E)-
- CAS REGISTRY NUMBER :
- 107-93-7
- BEILSTEIN REFERENCE NO. :
- 1719943
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C4-H6-O2
- MOLECULAR WEIGHT :
- 86.10
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 10 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 279,75,1992
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H318
[ Precautionary Statements ]:
P280-P305 + P351 + P338 + P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38;R50/53
[ Safety Phrases ]:
S26-S37/39-S61
[ RIDADR ]:
UN 2823
[ WGK Germany ]:
3
[ RTECS ]:
GQ2900000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
29161940
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29161940
Articles
Nat. Chem. Biol. 5 , 465-7, (2009)
We have isolated the small, highly strained carboxylic acid cycloprop-2-ene carboxylic acid from the Asian toxic mushroom Russula subnigricans. This compound is responsible for fatal rhabdomyolysis, a...
Chemical renal medullectomy. Effect on urinary prostaglandin E2 and plasma renin in response to variations in sodium intake and in relation to blood pressure.Hypertension 5(6) , 951-7, (1983)
We have studied the possible vasodepressor role of the renal medulla by chemical medullectomy. Bromoethylamine hydrobromide (200 mg/kg) was injected to induce selective renal medullary necrosis in rat...
Using organic acids to control subacute ruminal acidosis and fermentation in feedlot cattle fed a high-grain diet.J. Anim. Sci. 93 , 3950-8, (2015)
The objective of this study was to determine whether supplementing organic acids can prevent incidences of subacute ruminal acidosis (SARA) in beef heifers fed a diet consisting of 8% barley silage an...