n-octanoyl-dl-homoserine lactone

Names

[ Name ]:
n-octanoyl-dl-homoserine lactone

[Synonym ]:
N-CAPRYLOYL-DL-HOMOSERINE LACTONE
N-octanoylhomoserine lactone
N-Octanoyl-DL-homoserine lactone
3-octanoylamino-dihydro-furan-2-one

Biological Activity

[Description]:

N-Octanoyl-DL-homoserine lactone is a member of N-acyl homoserine lactones (AHLs) family, also one of the signal molecule of quorum-sensing (QS) signals. N-Octanoyl-DL-homoserine lactone can regulate the production of siderophores and present positive correlation in Aeromonas sobria strain AS7. N-Octanoyl-DL-homoserine lactone can also regulate the secretion of proteases and stimulate the production of total volatile basic nitrogen (TVB-N)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Li T, et al. Involvement of Acylated Homoserine Lactones (AHLs) of Aeromonas sobria in Spoilage of Refrigerated Turbot (Scophthalmus maximus L.). Sensors (Basel). 2016 Jul 13;16(7):1083.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₂₁NO₃

[ Molecular Weight ]:
227.30000

[ Exact Mass ]:
227.15200

[ PSA ]:
55.40000

[ LogP ]:
2.16950

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones.

Microbiology 143 , 3703, (1997)

Quorum sensing relies upon the interaction of a diffusible signal molecule with a transcriptional activator protein to couple gene expression with cell population density. In Gram-negative bacteria, s...

Quorum sensing in the genus Burkholderia.

Int. J. Med. Microbiol. 296 , 103-110, (2006)

The genus Burkholderia contains over 30 species, many of which are important human pathogens. In addition to the primary pathogens Burkholderia pseudomallei and Burkholderia mallei, several species ha...

Quorum sensing-dependent regulation and blockade of exoprotease production in Aeromonas hydrophila.

Infect. Immun. 67 , 5192-5199, (1999)

In Aeromonas hydrophila, the ahyI gene encodes a protein responsible for the synthesis of the quorum sensing signal N-butanoyl-L-homoserine lactone (C4-HSL). Inactivation of the ahyI gene on the A. hy...