7-Amino-4-methylcoumarin-3-acetic acid

Names

[ Name ]:
7-Amino-4-methylcoumarin-3-acetic acid

[Synonym ]:
AMCA-H
2H-1-Benzopyran-3-acetic acid,AMCA-H,Aminomethyl coumarin acetic acid
7-amino-4-methylcoumarine-3-acetic acid
MFCD00081051
7-amino-4-methylcumarin-3-acetic acid
2H-1-Benzopyran-3-acetic acid AMCA-H Aminomethyl coumarin acetic acid
7-Amino-4-methyl-3-coumarinylacetic acid
7-Amino-4-methylcoumarin-3-acetic Acid
2-(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid
2H-1-Benzopyran-3-aceticacid,7-amino-4-methyl-2-oxo
AMCA-H [7-Amino-4-methyl-3-coumarinylacetic acid ]

Biological Activity

[Description]:

7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Khalfan H, et al. Aminomethyl coumarin acetic acid: a new fluorescent labelling agent for proteins. Histochem J. 1986;18(9):497-499.

Chemical & Physical Properties

[ Density]:
1.391g/cm3

[ Boiling Point ]:
512.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₂H₁₁NO₄

[ Molecular Weight ]:
233.22000

[ Flash Point ]:
263.6ºC

[ Exact Mass ]:
233.06900

[ PSA ]:
93.53000

[ LogP ]:
1.89190

[ Vapour Pressure ]:
2.58E-11mmHg at 25°C

[ Index of Refraction ]:
1.629

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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