<Suppliers Price>

Tubulin inhibitor 6

Names

[ CAS No. ]:
105925-39-1

[ Name ]:
Tubulin inhibitor 6

[Synonym ]:
MFCD01245092

Biological Activity

[Description]:

Tubulin inhibitor 6 (Compound 14b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 6 inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 inhibits K562 cell growth with an IC50 of 840 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin
Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[Target]

IC50: 0.87 μM (tubulin polymerization)[1]


[In Vitro]

Tubulin inhibitor 6 displays submicromolar antiproliferative activity[1].

[References]

[1]. Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H14ClNO2S

[ Molecular Weight ]:
367.85

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds