Prasugrel chloride impurity

Names

[ Name ]:
Prasugrel chloride impurity

[Synonym ]:
2-Pentanone, 1-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-5-chloro-1-(2-fluorophenyl)-
5-[5-Chloro-1-(2-fluorophenyl)-2-oxopentyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate

Biological Activity

[Description]:

Prasugrel chloride impurity is a catp impurity of Prasugrel, exacted from patent US20130345428A1, line 0053. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Hiroyuki Miyata, et al. Method for production of prasugrel hydrochloride having high purity. US20130345428A1.

[2]. Sugidachi A, et al. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost. 2007 Jul;5(7):1545-51.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
522.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₁ClFNO₃S

[ Molecular Weight ]:
409.902

[ Flash Point ]:
269.8±30.1 °C

[ Exact Mass ]:
409.091461

[ PSA ]:
74.85000

[ LogP ]:
3.79

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.583

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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