9H-Purine-2,6-diamine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-

Names

[ Name ]:
9H-Purine-2,6-diamine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-

[Synonym ]:
2,6-diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)purine
2-amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine
2,6-diamino-9-(2-fluoro-β-D-arabinosyl)purine

Biological Activity

[Description]:

2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₃FN₆O₃

[ Molecular Weight ]:
284.25

[ Exact Mass ]:
284.10300

[ PSA ]:
145.33000

Related Compounds

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